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KMID : 0387420090200030205
Korean Society of Oriental Neuropsychiatry
2009 Volume.20 No. 3 p.205 ~ p.216
Analysis of Studies on Guibi-tang(Guipitang) for Fundamental Establishment of Evidence Based Medicine(EBM)
Kim Jung-Hoon

Lee Jun-Kyoung
Ha Hye-Kyung
Seo Chang-Seob
Lee Mee-Young
Lee Ho-Young
Jung Da-Young
Lee Nam-Hun
Lee Jin-Ah
Huang Dae-Sun
Shin Hyeun-Kyoo
Abstract
Objectives: To establish the fundaments for EBM of Traditional Korean Medicine, the papers on Guibi-tang(Guipitang) which were frequently used in medical institutions of Traditional Korean Medicine were analyzed through researching domestic and international literatures.

Methods: The papers were classified by the year of publishment, by experimental methods, by laboratory animals used in biological experiment and by the kinds of studies on biological efficacy.

Results: Of total 39 papers were registered in domestic journals. Since 1980, publishments of papers have continuously increased. The papers on biological studies were 34 volumes, clinical studies were 5 volumes. Biological studies mainly showed the effects of anti-stress, anti-oxidant, hemostasis, anti-osteoporosis, gastroprotection, reproductive ability, brain cell activity, radioprotection. And clinical studies showed improvements of fearful throbbing, memory and orientation, insomnia, vericose vein, schizophrenia.

Conclusions: Guibi-tang(Guipitang) could be used to fortify the spleen, nourish the heart and then control the blood. However biological studies need to be conducted in accordance with clinical study and further clinical studies on randomized controlled trials should be proceeded.
KEYWORD
EBM, Guibi-tang(Guipitang), Biological study, Clinical study
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